Publications: 1974 – 1980



Langer, R., Rhine, W., Hsieh, D., Bawa, R.”Polymers for Sustained Macromolecule Release: Applications and Control of Release Kinetics”, J. Pharma. Sci.; 69, 265-270, 1980.

Conn, H., Berman, M., Kenyon, K., Langer, R., Gage, J. “Stromal vascularization prevents corneal ulceration”, Invest. Ophthal.; 19: 362-370, 1980.

Creque, H., Langer, R., Folkman, J.”One month sustained release of insulin from a polymer implant”, Diabetes; 29: 37-41, 1980.

Langer, R., Fefferman, M., Gryska, P., Berman, K.”A simple method for studying chemotaxis using sustained release of attractants from inert polymers”, Can. J. Microbiol.; 26: 274-278, 1980.

Langer, R., Conn, H., Vacanti, J., Haudenschild, C., Folkman, J.”Control of tumor growth in animals by infusion of an angiogenesis inhibitor”, Proceedings of the National Academy of Sciences; 77: 4331-4335, 1980.

Langer, R.”Polymeric delivery systems for controlled drug release”, Chem. Eng. Commun.; 6: 1-48, 1980.

Langer, R., Folkman, J.”Controlled release of macromolecules from polymers”, Biomedical Poly.; 113-139, 1980.

Langer, R., Rhine, W., Hsieh, D., Bawa, R.”Polymers for the sustained release of macromolecules: applications and control of release kinetics”, Controlled Rel. of Bioactive Mat.; 83-98, 1980.

Langer, R., Rhine, W., Hsich, D., Folkman, J.”Control of release kinetics of macromolecules from polymers”, J. Memb. Sci.; 7: 333-350, 1980.

Rhine, W. Sukhatme, V., Hsieh, D., Langer, R.”A new approach to achieve zero-order release kinetics from diffusion-controlled polymer matrix systems”, Cont. Rel. of Bioactive Mat.; 177-188, 1980.



Augustin, A., Langer, R.”Inhibitors to tumor vascularization and their delivery systems: possible extension to diabetes research”, Ocular and Systemic Disorders; 33-36, 1979.

Tapper, D., Langer, R., Conn, H., Folkman, J.”Oxygen content determined by acrylamide polymerization: screening of anticancer agents, generation of oxyhemoglobin dissociation curves, and potential applications”, Ann. Surg.; 189: 275-283, 1979.

Preis, I., Langer, R.”A Single-Step Immunization by Sustained Antigen Release”, Journal of Immunological Methods; 28 193-197, 1979.

Tapper, D., Langer, R., Bellows, A., Folkman, J.”Angiogenesis capacity as a diagnostic marker for human eye tumors”, Surgery; 86: 36-40, 1979.

Preis, I., Langer, R.”A single step immunization by sustained antigen release”, J. Immunol. Meth.; 28: 193-197, 1979.



Conn, H., Langer, R”Continuous long-term intra-arterial infusion in the unrestrained rabbit”, Lab. Anim. Sci.; 28: 598-602, 1978.

Langer, R., Folkman, J”Sustained release of macromolecules from polymers”, Poly. Del. Systems, Midland Macro. Monograph; 5: 175-196, 1978.



Brem, S., Preis, I., Langer, R., Brem, H., Folkman, J., Patz, A.”Inhibition of neovascularization by an extract derived From vitreous”, Am. J. Ophthal.; 84: 323-328, 1977.

Klagsbrun, M., Langer, R., Levenson, R., Smith, S., Lillehei, C.”The stimulation of DNA synthesis and cell division in chondrocytes and 3T3 cells by a growth factor isolated from cartilage”, Exp. Cell Res.; 105: 99-108, 1977.

Langer, R., Gardner, C., Hamilton, B., Colton, C.”Enzymatic regeneration of ATP II: equilibrium studies with acetate kinase and adenylate kinase”, AIChE J.; 23: 1-10, 1977.

Nemet, M., Solomon, B., Langer, R., Colton, C”Enzymatic regeneration of ATP from AMP and ADP: III kinetic studies with the coupled enzyme system”, Enzyme Eng.; 3: 85-91, 1977.



Gardner, C., Langer, R., Colton, C.”Dependence of pH of the hydroxylamine assay for acyl phosphates”, Anal. Biochem.; 76: 654-656, 1976.

Kessler, D., Langer, R., Pless, N., Folkman, J.”Mast cells and tumor angiogenesis”, Int. J. Cancer; 18: 703-709, 1976.

Langer, R., Hamilton, B., Gardner, C. Archer, M., Colton, C. Enzymatic regeneration of ATP I alternative routes. AIChE J., 22: 1079-1090, 1976.”Enzymatic regeneration of ATP I alternative routes”, AIChE J.; 22: 1079-1090, 1976.

Langer, R., Brem, H., Falterman, K., Klein, M., Folkman, J”Isolation of a cartilage factor that inhibits tumor neovascularization”, Science; 193: 70-72, 1976.

Langer, R., Folkman, J.”Polymers for the sustained release of proteins and other macromolecules”, Nature; 263: 797-800, 1976.



Gardner, C., Colton, C., Langer, R., Hamilton, B., Archer, M., Whitesides, G. “Enzymatic regeneration of ATP from AMP and ADP I. thermodynamics, kinetics, and process development, in Enzyme Engin.”, Enzyme Eng.; 2: 209-216, 1974.